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In vitro investigation of metabolic fate of α-mangostin and gartanin via skin permeation by LC-MS/MS and in silico evaluation of the metabolites by ADMET predictor™

BACKGROUND: Mangosteen, Garciniam angostana L., is a juicy fruit commonly found in Thailand. The rinds of Garciniam angostana L.have been used as a traditional medicine for the treatment of trauma, diarrhea and skin infection. It is also used in dermatological product such as in cosmetics. The mango...

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Detalles Bibliográficos
Autores principales: Rukthong, P., Sereesongsang, N., Kulsirirat, T., Boonnak, N., Sathirakul, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685627/
https://www.ncbi.nlm.nih.gov/pubmed/33228689
http://dx.doi.org/10.1186/s12906-020-03144-7