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Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway

BACKGROUND: Thymocyte-expressed, positive selection-associated 1 (Tespa1) is a critical signaling molecule in thymocyte development. This study aimed to investigate the regulatory effect of Tespa1 on mast cells in the pathogenesis of asthma and its relationship with the interleukin (IL)-4/signal tra...

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Detalles Bibliográficos
Autores principales: Yang, Ruhui, Wang, Guangli, Li, Lingyun, He, Hanjiang, Zheng, Mingzhu, Lu, Linrong, Wu, Songquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685668/
https://www.ncbi.nlm.nih.gov/pubmed/33228696
http://dx.doi.org/10.1186/s12967-020-02621-4