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Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway
BACKGROUND: Thymocyte-expressed, positive selection-associated 1 (Tespa1) is a critical signaling molecule in thymocyte development. This study aimed to investigate the regulatory effect of Tespa1 on mast cells in the pathogenesis of asthma and its relationship with the interleukin (IL)-4/signal tra...
Autores principales: | Yang, Ruhui, Wang, Guangli, Li, Lingyun, He, Hanjiang, Zheng, Mingzhu, Lu, Linrong, Wu, Songquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685668/ https://www.ncbi.nlm.nih.gov/pubmed/33228696 http://dx.doi.org/10.1186/s12967-020-02621-4 |
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