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Nanoparticle-complexed antimiRs for inhibiting tumor growth and metastasis in prostate carcinoma and melanoma

BACKGROUND: MiRNAs act as negative regulators of gene expression through target mRNA degradation or inhibition of its translation. In cancer, several miRNAs are upregulated and play crucial roles in tumorigenesis, making the inhibition of these oncomiRs an interesting therapeutic approach. This can...

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Detalles Bibliográficos
Autores principales: Kunz, Manfred, Brandl, Madeleine, Bhattacharya, Animesh, Nobereit-Siegel, Lars, Ewe, Alexander, Weirauch, Ulrike, Hering, Doreen, Reinert, Anja, Kalwa, Hermann, Guzman, Juan, Weigelt, Katrin, Wach, Sven, Taubert, Helge, Aigner, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685669/
https://www.ncbi.nlm.nih.gov/pubmed/33228711
http://dx.doi.org/10.1186/s12951-020-00728-w