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Bruton’s Tyrosine Kinase Inhibition Promotes Myelin Repair

BACKGROUND: Microglia are the resident macrophages of the central nervous system (CNS). In multiple sclerosis (MS) and related experimental models, microglia have either a pro-inflammatory or a pro-regenerative/pro-remyelinating function. Inhibition of Bruton’s tyrosine kinase (BTK), a member of the...

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Detalles Bibliográficos
Autores principales: Martin, Elodie, Aigrot, Marie-Stéphane, Grenningloh, Roland, Stankoff, Bruno, Lubetzki, Catherine, Boschert, Ursula, Zalc, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685672/
https://www.ncbi.nlm.nih.gov/pubmed/33282676
http://dx.doi.org/10.3233/BPL-200100