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Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross
Sequence variation in regulatory DNA alters gene expression and shapes genetically complex traits. However, the identification of individual, causal regulatory variants is challenging. Here, we used a massively parallel reporter assay to measure the cis-regulatory consequences of 5832 natural DNA va...
Autores principales: | Renganaath, Kaushik, Chong, Rockie, Day, Laura, Kosuri, Sriram, Kruglyak, Leonid, Albert, Frank W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685706/ https://www.ncbi.nlm.nih.gov/pubmed/33179598 http://dx.doi.org/10.7554/eLife.62669 |
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