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An in silico LLPS perturbation approach in the design of a novel SARS-CoV-2 spike receptor-binding domain inhibitor

The reversible process where a homogenous fluid de-mixes into two distinctively separate liquid phases is referred to as LLPS (Liquid-liquid phase separation). The resulting liquid is made up of one dilute phase and one condensed phase. An increasing number of studies have shown that the liquid-liqu...

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Detalles Bibliográficos
Autores principales: Durojaye, Olanrewaju Ayodeji, Sedzro, Divine Mensah, Mushiana, Talifhani, Uzoeto, Henrietta Onyinye, Cosmas, Samuel, Ajima, Judith Nnedimkpa, Ibiang, Glory Omini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685779/
http://dx.doi.org/10.1186/s43042-020-00105-0