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An in silico LLPS perturbation approach in the design of a novel SARS-CoV-2 spike receptor-binding domain inhibitor
The reversible process where a homogenous fluid de-mixes into two distinctively separate liquid phases is referred to as LLPS (Liquid-liquid phase separation). The resulting liquid is made up of one dilute phase and one condensed phase. An increasing number of studies have shown that the liquid-liqu...
Autores principales: | Durojaye, Olanrewaju Ayodeji, Sedzro, Divine Mensah, Mushiana, Talifhani, Uzoeto, Henrietta Onyinye, Cosmas, Samuel, Ajima, Judith Nnedimkpa, Ibiang, Glory Omini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685779/ http://dx.doi.org/10.1186/s43042-020-00105-0 |
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