Mesenchymal Stem Cells Activate the MEK/ERK Signaling Pathway and Enhance DNA Methylation via DNMT1 in PBMC from Systemic Lupus Erythematosus

The defective MEK/ERK signaling pathway and downstream hypomethylation pattern of lymphocytes are crucial for the pathogenesis of systemic lupus erythematosus (SLE). However, the role that the mesenchymal stem cells play in the MEK/ERK signaling pathway and DNA methylation of peripheral blood mononu...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Hui, Guo, Zhixuan, Tang, Zengqi, Ai, Xuechen, Qi, Qing, Liu, Xiuting, Huang, Danqi, Li, Zhaofeng, Ji, Suyun, Guo, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685810/
https://www.ncbi.nlm.nih.gov/pubmed/33282947
http://dx.doi.org/10.1155/2020/4174082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685810/
https://www.ncbi.nlm.nih.gov/pubmed/33282947
http://dx.doi.org/10.1155/2020/4174082

Ejemplares similares