Tackling the COVID-19 “cytokine storm” with microRNA mimics directly targeting the 3’UTR of pro-inflammatory mRNAs

COVID-19 is characterized by two major clinical phases, the SARS-CoV-2 infection of target cells and tissues, and a deep inflammatory state, known as “cytokine storm”, caused by activation of pro-inflammatory genes, such as NF-kB, STAT-3, IL-6, IL-8, IL-1ß. Among possible anti-inflammatory agents, t...

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Detalles Bibliográficos
Autores principales: Gasparello, Jessica, Finotti, Alessia, Gambari, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685948/
https://www.ncbi.nlm.nih.gov/pubmed/33422363
http://dx.doi.org/10.1016/j.mehy.2020.110415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685948/
https://www.ncbi.nlm.nih.gov/pubmed/33422363
http://dx.doi.org/10.1016/j.mehy.2020.110415

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