Chromatin remodeler Znhit1 preserves hematopoietic stem cell quiescence by determining the accessibility of distal enhancers

Hematopoietic stem cell (HSC) utilizes its quiescence feature to combat exhaustion for lifetime blood cell supply. To date, how certain chromatin architecture and subsequent transcription profile permit HSC quiescence remains unclear. Here, we show an essential role of chromatin remodeler zinc finge...

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Detalles Bibliográficos
Autores principales: Sun, Shenfei, Jiang, Ning, Jiang, Yamei, He, Qiuping, He, Hua, Wang, Xin, Yang, Li, Li, Runsheng, Liu, Feng, Lin, Xinhua, Zhao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685981/
https://www.ncbi.nlm.nih.gov/pubmed/32694618
http://dx.doi.org/10.1038/s41375-020-0988-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685981/
https://www.ncbi.nlm.nih.gov/pubmed/32694618
http://dx.doi.org/10.1038/s41375-020-0988-5

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