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MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer

Head and Neck Squamous Cell Cancer (HNSCC) presents with multiple treatment challenges limiting overall survival rates and affecting patients' quality of life. Amongst these, resistance to radiation therapy constitutes a major clinical problem in HNSCC patients compounded by origin, location, a...

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Detalles Bibliográficos
Autores principales: Shukla, Kirtikar, Singh, Naveen, Lewis, Joshua E., Tsang, Allen W., Boothman, David A., Kemp, Melissa L., Furdui, Cristina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685994/
https://www.ncbi.nlm.nih.gov/pubmed/33262939
http://dx.doi.org/10.3389/fonc.2020.536377