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MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer
Head and Neck Squamous Cell Cancer (HNSCC) presents with multiple treatment challenges limiting overall survival rates and affecting patients' quality of life. Amongst these, resistance to radiation therapy constitutes a major clinical problem in HNSCC patients compounded by origin, location, a...
Autores principales: | Shukla, Kirtikar, Singh, Naveen, Lewis, Joshua E., Tsang, Allen W., Boothman, David A., Kemp, Melissa L., Furdui, Cristina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685994/ https://www.ncbi.nlm.nih.gov/pubmed/33262939 http://dx.doi.org/10.3389/fonc.2020.536377 |
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