Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions

Human induced pluripotent stem cell (hiPSC)‐derived blood‐brain barrier (BBB) models established to date lack expression of key adhesion molecules involved in immune cell migration across the BBB in vivo. Here, we introduce the extended endothelial cell culture method (EECM), which differentiates hi...

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Detalles Bibliográficos
Autores principales: Nishihara, Hideaki, Gastfriend, Benjamin D., Soldati, Sasha, Perriot, Sylvain, Mathias, Amandine, Sano, Yasuteru, Shimizu, Fumitaka, Gosselet, Fabien, Kanda, Takashi, Palecek, Sean P., Du Pasquier, Renaud, Shusta, Eric V., Engelhardt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686106/
https://www.ncbi.nlm.nih.gov/pubmed/33124083
http://dx.doi.org/10.1096/fj.202001507RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686106/
https://www.ncbi.nlm.nih.gov/pubmed/33124083
http://dx.doi.org/10.1096/fj.202001507RR

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