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Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions
Human induced pluripotent stem cell (hiPSC)‐derived blood‐brain barrier (BBB) models established to date lack expression of key adhesion molecules involved in immune cell migration across the BBB in vivo. Here, we introduce the extended endothelial cell culture method (EECM), which differentiates hi...
Autores principales: | Nishihara, Hideaki, Gastfriend, Benjamin D., Soldati, Sasha, Perriot, Sylvain, Mathias, Amandine, Sano, Yasuteru, Shimizu, Fumitaka, Gosselet, Fabien, Kanda, Takashi, Palecek, Sean P., Du Pasquier, Renaud, Shusta, Eric V., Engelhardt, Britta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686106/ https://www.ncbi.nlm.nih.gov/pubmed/33124083 http://dx.doi.org/10.1096/fj.202001507RR |
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