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Mechanical Strain Induces Phenotypic Changes in Breast Cancer Cells and Promotes Immunosuppression in the Tumor Microenvironment

Breast cancer (BCa) proliferates within a complex, three-dimensional microenvironment amid heterogeneous biochemical and biophysical cues. Understanding how mechanical forces within the tumor microenvironment (TME) regulate BCa phenotype is of great interest. We demonstrate that mechanical strain en...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Goliwas, Kayla F., Severino, Paige E., Hough, Kenneth, Van Vessem, Derek, Wang, Hong, Tousif, Sultan, Koomullil, Roy P., Frost, Andra R., Ponnazhagen, Selvarangan, Berry, Joel L., Deshane, Jessy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686122/
https://www.ncbi.nlm.nih.gov/pubmed/32572176
http://dx.doi.org/10.1038/s41374-020-0452-1