Cargando…

Mechanical Strain Induces Phenotypic Changes in Breast Cancer Cells and Promotes Immunosuppression in the Tumor Microenvironment

Breast cancer (BCa) proliferates within a complex, three-dimensional microenvironment amid heterogeneous biochemical and biophysical cues. Understanding how mechanical forces within the tumor microenvironment (TME) regulate BCa phenotype is of great interest. We demonstrate that mechanical strain en...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yong, Goliwas, Kayla F., Severino, Paige E., Hough, Kenneth, Van Vessem, Derek, Wang, Hong, Tousif, Sultan, Koomullil, Roy P., Frost, Andra R., Ponnazhagen, Selvarangan, Berry, Joel L., Deshane, Jessy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686122/ https://www.ncbi.nlm.nih.gov/pubmed/32572176 http://dx.doi.org/10.1038/s41374-020-0452-1

Ejemplares similares

Computational Simulation of Exosome Transport in Tumor Microenvironment
por: Koomullil, Roy, et al.
Publicado: (2021)

Extracellular Vesicles: Bidirectional Accelerators of Cellular Senescence in Fibrosis?
por: Goliwas, Kayla F., et al.
Publicado: (2020)

Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer Model
por: Goliwas, Kayla F., et al.
Publicado: (2021)

Sphingolipids in Lung Pathology in the Coronavirus Disease Era: A Review of Sphingolipid Involvement in the Pathogenesis of Lung Damage
por: Khan, Saad A., et al.
Publicado: (2021)

Indoleamine 2, 3-Dioxygenase Promotes Aryl Hydrocarbon Receptor-Dependent Differentiation Of Regulatory B Cells in Lung Cancer
por: Tousif, Sultan, et al.
Publicado: (2021)

The dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer
por: Sawant, Anandi, et al.
Publicado: (2014)

Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment
por: Schafer, Cara C., et al.
Publicado: (2016)

Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization
por: Pritchard, Alexandra, et al.
Publicado: (2020)

A recapitulative three-dimensional model of breast carcinoma requires perfusion for multi-week growth
por: Goliwas, Kayla F, et al.
Publicado: (2016)

Altered sphingolipid pathway in SARS-CoV-2 infected human lung tissue
por: Khan, Rabisa J., et al.
Publicado: (2023)

Extracellular Vesicles as Mediators of Cellular Cross Talk in the Lung Microenvironment
por: Bartel, Sabine, et al.
Publicado: (2020)

Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment
por: Moore-Smith, Lakisha D., et al.
Publicado: (2017)

Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer Model
por: Goliwas, Kayla F., et al.
Publicado: (2017)

Ex Vivo Modeling of Human Neuroendocrine Tumors in Tissue Surrogates
por: Herring, Brendon, et al.
Publicado: (2021)

Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells()
por: Hough, Kenneth P., et al.
Publicado: (2018)

Airway Remodeling in Asthma
por: Hough, Kenneth P., et al.
Publicado: (2020)

“Stick a Fork in Me; I’m Done”: Epithelial Cell Expression of ORMDL Sphingolipid Biosynthesis Regulator 3 Mediates Autophagic Cell Death
por: Curtiss, Miranda L., et al.
Publicado: (2022)

Immunosuppressive Microenvironment in Neuroblastoma
por: Pistoia, Vito, et al.
Publicado: (2013)

Mitochondrial transfer from cancer-associated fibroblasts increases migration in aggressive breast cancer
por: Goliwas, Kayla F., et al.
Publicado: (2023)

The case for well-conducted experiments to validate statistical protocols for 2D gels: different pre-processing = different lists of significant proteins
por: Meleth, Sreelatha, et al.
Publicado: (2005)

The immunosuppressive microenvironment and immunotherapy in human glioblastoma
por: Zhang, Xuehua, et al.
Publicado: (2022)

Modes of immunosuppression in glioblastoma microenvironment
por: Lehtipuro, Suvi, et al.
Publicado: (2019)

Role of the immunosuppressive microenvironment in immunotherapy
por: Tormoen, Garth W., et al.
Publicado: (2018)

Cancer Stem Cells and Immunosuppressive Microenvironment in Glioma
por: Ma, Qianquan, et al.
Publicado: (2018)

The roles of curcumin in regulating the tumor immunosuppressive microenvironment
por: Wang, Yizhi, et al.
Publicado: (2020)

Harnessing nanomedicine to overcome the immunosuppressive tumor microenvironment
por: Sun, Bo, et al.
Publicado: (2020)

Immunosuppressive Roles of Galectin-1 in the Tumor Microenvironment
por: Huang, Yanyu, et al.
Publicado: (2021)

Advances in Hypofractionated Irradiation-Induced Immunosuppression of Tumor Microenvironment
por: Wang, Yuxia
Publicado: (2021)

Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma
por: DeCordova, Syreeta, et al.
Publicado: (2020)

Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma
por: Molina, Maria L., et al.
Publicado: (2019)

Exosome-Mediated Immunosuppression in Tumor Microenvironments
por: Xie, Qi-Hui, et al.
Publicado: (2022)

The Influence of the Cancer Microenvironment on the Process of Metastasis
por: Frost, Andra R., et al.
Publicado: (2012)

Clinical Outcomes in COVID-19 Patients Treated with Immunotherapy
por: Hatic, Haris, et al.
Publicado: (2022)

Differences in airway microbiome and metabolome of single lung transplant recipients
por: Sharma, Nirmal S., et al.
Publicado: (2020)

Immunoprofiling in Neuroendocrine Neoplasms Unveil Immunosuppressive Microenvironment
por: Busse, Antonia, et al.
Publicado: (2020)

Hypoxic Characteristic in the Immunosuppressive Microenvironment of Hepatocellular Carcinoma
por: Mo, Zhuomao, et al.
Publicado: (2021)

Overcoming the Immunosuppressive Tumor Microenvironment in Multiple Myeloma
por: Uckun, Fatih M.
Publicado: (2021)

Glioblastoma: Relationship between Metabolism and Immunosuppressive Microenvironment
por: Hernández, Ainhoa, et al.
Publicado: (2021)

An integrated overview of the immunosuppression features in the tumor microenvironment of pancreatic cancer
por: Guo, Jinglong, et al.
Publicado: (2023)

Overexpression of SMS in the tumor microenvironment is associated with immunosuppression in hepatocellular carcinoma
por: Xiang, Lin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_brt9d4dblrahvqh3rc4mcn8e4j