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Efficacy and safety of Dentoxol® in the prevention of radiation-induced oral mucositis in head and neck cancer patients (ESDOM): a randomized, multicenter, double-blind, placebo-controlled, phase II trial

PURPOSE: The aim of this study was to assess the efficacy and safety of Dentoxol mouthrinse in reducing the severity of oral mucositis (OM) secondary to radiation therapy (RT) for head and neck cancer. METHODS: A randomized, double-blind, placebo-controlled, multicenter phase II clinical trial was c...

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Detalles Bibliográficos
Autores principales: Lalla, Rajesh V., Solé, Sebastián, Becerra, Sergio, Carvajal, Claudia, Bettoli, Piero, Letelier, Hernán, Santini, Alejandro, Vargas, Lorena, Cifuentes, Alexander, Larsen, Francisco, Jara, Natalia, Oyarzún, Jorge, Feinn, Richard, Bustamante, Eva, Martínez, Benjamín, Rosenberg, David, Galván, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686187/
https://www.ncbi.nlm.nih.gov/pubmed/32266567
http://dx.doi.org/10.1007/s00520-020-05358-4