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High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli
Understanding the constraints that shape the evolution of antibiotic resistance is critical for predicting and controlling drug resistance. Despite its importance, however, a systematic investigation of evolutionary constraints is lacking. Here, we perform a high-throughput laboratory evolution of E...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686311/ https://www.ncbi.nlm.nih.gov/pubmed/33235191 http://dx.doi.org/10.1038/s41467-020-19713-w |