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Immortalisation of primary human alveolar epithelial lung cells using a non-viral vector to study respiratory bioreactivity in vitro

To overcome the scarcity of primary human alveolar epithelial cells for lung research, and the limitations of current cell lines to recapitulate the phenotype, functional and molecular characteristics of the healthy human alveolar epithelium, we have developed a new method to immortalise primary hum...

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Detalles Bibliográficos
Autores principales: Katsumiti, Alberto, Ruenraroengsak, Pakatip, Cajaraville, Miren P., Thorley, Andrew J., Tetley, Teresa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686381/
https://www.ncbi.nlm.nih.gov/pubmed/33235275
http://dx.doi.org/10.1038/s41598-020-77191-y