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Complex fibroblast response to glucocorticoids may underlie variability of clinical efficacy in the vocal folds
Similar to the hypertrophic scar and keloids, the efficacy of glucorticoids (GC) for vocal fold injury is highly variable. We previously reported dexamethasone enhanced the pro-fibrotic effects of transforming growth factor (TGF)-β as a potential mechanism for inconsistent clinical outcomes. In the...
Autores principales: | Nakamura, Ryosuke, Mukudai, Shigeyuki, Bing, Renjie, Garabedian, Michael J., Branski, Ryan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686477/ https://www.ncbi.nlm.nih.gov/pubmed/33235235 http://dx.doi.org/10.1038/s41598-020-77445-9 |
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