Synthetic protein-binding DNA sponge as a tool to tune gene expression and mitigate protein toxicity

Versatile tools for gene expression regulation are vital for engineering gene networks of increasing scales and complexity with bespoke responses. Here, we investigate and repurpose a ubiquitous, indirect gene regulation mechanism from nature, which uses decoy protein-binding DNA sites, named DNA sp...

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Detalles Bibliográficos
Autores principales: Wan, Xinyi, Pinto, Filipe, Yu, Luyang, Wang, Baojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686491/
https://www.ncbi.nlm.nih.gov/pubmed/33235249
http://dx.doi.org/10.1038/s41467-020-19552-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686491/
https://www.ncbi.nlm.nih.gov/pubmed/33235249
http://dx.doi.org/10.1038/s41467-020-19552-9

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