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Synthetic protein-binding DNA sponge as a tool to tune gene expression and mitigate protein toxicity
Versatile tools for gene expression regulation are vital for engineering gene networks of increasing scales and complexity with bespoke responses. Here, we investigate and repurpose a ubiquitous, indirect gene regulation mechanism from nature, which uses decoy protein-binding DNA sites, named DNA sp...
Autores principales: | Wan, Xinyi, Pinto, Filipe, Yu, Luyang, Wang, Baojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686491/ https://www.ncbi.nlm.nih.gov/pubmed/33235249 http://dx.doi.org/10.1038/s41467-020-19552-9 |
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