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High CD45 expression of CD8+ and CD4+ T cells correlates with the size of HIV-1 reservoir in blood

Using mass cytometry, we investigated the expression of 28 markers on CD8+ and CD4+ T cells from HIV-1 infected patients with a variable size of HIV-1 reservoir defined as high (HR) and low (LR) reservoir; we aimed at identifying phenotypic associations of T cells with size of HIV-1 reservoir. We sh...

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Detalles Bibliográficos
Autores principales: Petkov, Stefan, Bekele, Yonas, Lakshmikanth, Tadepally, Hejdeman, Bo, Zazzi, Maurizio, Brodin, Petter, Chiodi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686502/
https://www.ncbi.nlm.nih.gov/pubmed/33235273
http://dx.doi.org/10.1038/s41598-020-77433-z