Syndecan-3 regulates MSC adhesion, ERK and AKT signalling in vitro and its deletion enhances MSC efficacy in a model of inflammatory arthritis in vivo

Rheumatoid arthritis (RA) is a debilitating and painful inflammatory autoimmune disease characterised by the accumulation of leukocytes in the synovium, cartilage destruction and bone erosion. The immunomodulatory effects of bone marrow derived mesenchymal stem cells (MSCs) has been widely studied a...

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Detalles Bibliográficos
Autores principales: Jones, Fiona K., Stefan, Andrei, Kay, Alasdair G., Hyland, Mairead, Morgan, Rebecca, Forsyth, Nicholas R., Pisconti, Addolorata, Kehoe, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686503/
https://www.ncbi.nlm.nih.gov/pubmed/33235244
http://dx.doi.org/10.1038/s41598-020-77514-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686503/
https://www.ncbi.nlm.nih.gov/pubmed/33235244
http://dx.doi.org/10.1038/s41598-020-77514-z

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