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Siplizumab, an Anti-CD2 Monoclonal Antibody, Induces a Unique Set of Immune Modulatory Effects Compared to Alemtuzumab and Rabbit Anti-Thymocyte Globulin In Vitro

Antibodies are commonly used in organ transplant induction therapy and to treat autoimmune disorders. The effects of some biologics on the human immune system remain incompletely characterized and a deeper understanding of their mechanisms of action may provide useful insights for their clinical app...

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Detalles Bibliográficos
Autores principales: Binder, Christian, Sellberg, Felix, Cvetkovski, Filip, Berglund, Erik, Berglund, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686512/
https://www.ncbi.nlm.nih.gov/pubmed/33262770
http://dx.doi.org/10.3389/fimmu.2020.592553