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A Window of Opportunity: Targeting Cancer Endothelium to Enhance Immunotherapy
Vascular abnormalities in tumors have a major impact on the immune microenvironment in tumors. The consequences of abnormal vasculature include increased hypoxia, acidosis, high intra-tumoral fluid pressure, and angiogenesis. This introduces an immunosuppressive microenvironment that alters immune c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686513/ https://www.ncbi.nlm.nih.gov/pubmed/33262763 http://dx.doi.org/10.3389/fimmu.2020.584723 |