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A Window of Opportunity: Targeting Cancer Endothelium to Enhance Immunotherapy

Vascular abnormalities in tumors have a major impact on the immune microenvironment in tumors. The consequences of abnormal vasculature include increased hypoxia, acidosis, high intra-tumoral fluid pressure, and angiogenesis. This introduces an immunosuppressive microenvironment that alters immune c...

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Detalles Bibliográficos
Autores principales: Duru, Gizem, van Egmond, Marjolein, Heemskerk, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686513/
https://www.ncbi.nlm.nih.gov/pubmed/33262763
http://dx.doi.org/10.3389/fimmu.2020.584723