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Simultaneous determination of calycosin, prim-O-glucosylcimifugin, and paeoniflorin in rat plasma by HPLC-MS/MS: application in the pharmacokinetic analysis of HQCF

OBJECTIVE: This study aimed to develop and validate a high-performance liquid chromatography–tandem mass spectrometry method to simultaneously determine three bioactive components of the Huangqi Chifeng decoction (HQCF) in rat plasma. METHODS: Taxol was used as an internal standard in the developed...

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Detalles Bibliográficos
Autores principales: Gu, Yulong, Piao, Xianglan, Zhu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686626/
https://www.ncbi.nlm.nih.gov/pubmed/33213240
http://dx.doi.org/10.1177/0300060520972902