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The higher the better? Defining the optimal beta-lactam target for critically ill patients to reach infection resolution and improve outcome

OBJECTIVES: Beta-lactam antibiotics are often subject to therapeutic drug monitoring, but breakpoints of target attainment are mostly based on expert opinions. Studies that show a correlation between target attainment and infection resolution are missing. This analysis investigated whether there is...

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Detalles Bibliográficos
Autores principales: Scharf, Christina, Liebchen, Uwe, Paal, Michael, Taubert, Max, Vogeser, Michael, Irlbeck, Michael, Zoller, Michael, Schroeder, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686672/
https://www.ncbi.nlm.nih.gov/pubmed/33292582
http://dx.doi.org/10.1186/s40560-020-00504-w