Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization

Cellular actin networks grow by ATP-actin addition at filament barbed ends and have long been presumed to depolymerize at their pointed ends, primarily after filaments undergo “aging” (ATP hydrolysis and P(i) release). The cytosol contains high levels of actin monomers, which favors assembly over di...

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Detalles Bibliográficos
Autores principales: Shekhar, Shashank, Hoeprich, Gregory J., Gelles, Jeff, Goode, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686915/
https://www.ncbi.nlm.nih.gov/pubmed/33226418
http://dx.doi.org/10.1083/jcb.202006022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686915/
https://www.ncbi.nlm.nih.gov/pubmed/33226418
http://dx.doi.org/10.1083/jcb.202006022

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