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Maackiain dampens osteoclastogenesis via attenuating RANKL‐stimulated NF‐κB signalling pathway and NFATc1 activity

Osteolytic diseases are typified by over‐enhanced formation and resorbing function of osteoclasts and have a major impact on human health. Inhibition of osteoclastic differentiation and function is a key strategy for clinical therapy of osteolytic conditions. Maackiain is a natural compound extracte...

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Detalles Bibliográficos
Autores principales: Liu, Yuhao, Zeng, Weizai, Ma, Chao, Wang, Ziyi, Wang, Chao, Li, Shaobin, He, Wei, Zhang, Qingwen, Xu, Jiake, Zhou, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686960/
https://www.ncbi.nlm.nih.gov/pubmed/32939977
http://dx.doi.org/10.1111/jcmm.15647