C‐Cbl regulates c‐MPL receptor trafficking and its internalization

Thrombocyte formation from megakaryocyte and their progenitor cells is tightly regulated by thrombopoietin (TPO) and its receptor c‐MPL, thereby maintaining physiological functionality and numbers of circulating platelets. In patients, dysfunction of this regulation could cause thrombocytopenia or m...

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Detalles Bibliográficos
Autores principales: Märklin, Melanie, Tandler, Claudia, Kopp, Hans‐Georg, Hoehn, Kyle L., Quintanilla‐Martinez, Leticia, Borst, Oliver, Müller, Martin R., Saur, Sebastian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687000/
https://www.ncbi.nlm.nih.gov/pubmed/32954656
http://dx.doi.org/10.1111/jcmm.15785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687000/
https://www.ncbi.nlm.nih.gov/pubmed/32954656
http://dx.doi.org/10.1111/jcmm.15785

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