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MicroRNA‐497 elevation or LRG1 knockdown promotes osteoblast proliferation and collagen synthesis in osteoporosis via TGF‐β1/Smads signalling pathway

MicroRNAs (miRNAs) have been corroborated to engage in the process of cellular activities in osteoporosis. However, few researches have been conducted to expose the integrated role of miR‐497, leucine‐rich alpha‐2‐glycoprotein‐1 (LRG1) and transforming growth factor beta 1 (TGF‐β1)/Smads signalling...

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Detalles Bibliográficos
Autores principales: Gu, ZhengTao, Xie, DengHui, Huang, CaiQiang, Ding, Rui, Zhang, RongKai, Li, QingChu, Lin, ChuangXin, Qiu, YiYan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687005/
https://www.ncbi.nlm.nih.gov/pubmed/32975015
http://dx.doi.org/10.1111/jcmm.15826