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Effect of structural stability on endolysosomal degradation and T‐cell reactivity of major shrimp allergen tropomyosin

BACKGROUND: Tropomyosins are highly conserved proteins, an attribute that forms the molecular basis for their IgE antibody cross‐reactivity. Despite sequence similarities, their allergenicity varies greatly between ingested and inhaled invertebrate sources. In this study, we investigated the relatio...

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Detalles Bibliográficos
Autores principales: Kamath, Sandip D., Scheiblhofer, Sandra, Johnson, Christopher M., Machado, Yoan, McLean, Thomas, Taki, Aya C., Ramsland, Paul A., Iyer, Swati, Joubert, Isabella, Hofer, Heidi, Wallner, Michael, Thalhamer, Josef, Rolland, Jennifer, O’Hehir, Robyn, Briza, Peter, Ferreira, Fatima, Weiss, Richard, Lopata, Andreas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687109/
https://www.ncbi.nlm.nih.gov/pubmed/32436591
http://dx.doi.org/10.1111/all.14410