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Efficacy and safety of humanized anti‐CD19‐CAR‐T therapy following intensive lymphodepleting chemotherapy for refractory/relapsed B acute lymphoblastic leukaemia

We studied the efficacy and safety of humanized CAR‐T therapy following intensive chemotherapy for refractory/relapsed (R/R) acute lymphoblastic leukaemia (B‐ALL). Twenty‐three patients with R/R B‐ALL were pretreated with intensive chemotherapy (fludarabine combined with medium‐dose cytarabine) 12 d...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Mou, Nan, Yang, Zhenxing, Li, Qing, Jiang, Yanyu, Meng, Juanxia, Liu, Xuxiang, Deng, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687133/
https://www.ncbi.nlm.nih.gov/pubmed/32232846
http://dx.doi.org/10.1111/bjh.16623