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SSSCPreds: Deep Neural Network-Based Software for the Prediction of Conformational Variability and Application to SARS-CoV-2

[Image: see text] Amino acid mutations that improve protein stability and rigidity can accompany increases in binding affinity. Therefore, conserved amino acids located on a protein surface may be successfully targeted by antibodies. The quantitative deep mutational scanning approach is an excellent...

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Detalles Bibliográficos
Autores principales: Izumi, Hiroshi, Nafie, Laurence A., Dukor, Rina K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687297/
https://www.ncbi.nlm.nih.gov/pubmed/33283104
http://dx.doi.org/10.1021/acsomega.0c04472