Quantitative in Vitro to in Vivo Extrapolation (QIVIVE) for Predicting Reduced Anogenital Distance Produced by Anti-Androgenic Pesticides in a Rodent Model for Male Reproductive Disorders

BACKGROUND: Many pesticides can antagonize the androgen receptor (AR) or inhibit androgen synthesis in vitro but their potential to cause reproductive toxicity related to disruption of androgen action during fetal life is difficult to predict. Currently no approaches for using in vitro data to antic...

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Detalles Bibliográficos
Autores principales: Scholze, Martin, Taxvig, Camilla, Kortenkamp, Andreas, Boberg, Julie, Christiansen, Sofie, Svingen, Terje, Lauschke, Karin, Frandsen, Henrik, Ermler, Sibylle, Hermann, Susan Strange, Pedersen, Mikael, Lykkeberg, Anne Kruse, Axelstad, Marta, Vinggaard, Anne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687371/
https://www.ncbi.nlm.nih.gov/pubmed/33236927
http://dx.doi.org/10.1289/EHP6774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687371/
https://www.ncbi.nlm.nih.gov/pubmed/33236927
http://dx.doi.org/10.1289/EHP6774

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