LRP1 is a master regulator of tau uptake and spread

The spread of protein aggregates during disease progression is a common theme underlying many neurodegenerative diseases. The microtubule-associated protein tau (MAPT) plays a central role in the pathogenesis of several forms of dementia known as tauopathies, including Alzheimer’s disease (AD), fron...

Descripción completa

Detalles Bibliográficos
Autores principales: Rauch, Jennifer N., Luna, Gabriel, Guzman, Elmer, Audouard, Morgane, Challis, Collin, Sibih, Youssef E., Leshuk, Carolina, Hernandez, Israel, Wegmann, Susanne, Hyman, Bradley T., Gradinaru, Viviana, Kampmann, Martin, Kosik, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687380/
https://www.ncbi.nlm.nih.gov/pubmed/32296178
http://dx.doi.org/10.1038/s41586-020-2156-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687380/
https://www.ncbi.nlm.nih.gov/pubmed/32296178
http://dx.doi.org/10.1038/s41586-020-2156-5

Ejemplares similares