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LRP1 is a master regulator of tau uptake and spread

The spread of protein aggregates during disease progression is a common theme underlying many neurodegenerative diseases. The microtubule-associated protein tau (MAPT) plays a central role in the pathogenesis of several forms of dementia known as tauopathies, including Alzheimer’s disease (AD), fron...

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Detalles Bibliográficos
Autores principales:	Rauch, Jennifer N., Luna, Gabriel, Guzman, Elmer, Audouard, Morgane, Challis, Collin, Sibih, Youssef E., Leshuk, Carolina, Hernandez, Israel, Wegmann, Susanne, Hyman, Bradley T., Gradinaru, Viviana, Kampmann, Martin, Kosik, Kenneth S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687380/ https://www.ncbi.nlm.nih.gov/pubmed/32296178 http://dx.doi.org/10.1038/s41586-020-2156-5

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