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Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses

Various vaccine strategies have been proposed in response to the global COVID-19 pandemic, each with unique strategies for eliciting immune responses. Here, we developed nanoparticle vaccines by covalently conjugating the self-assembled 24-mer ferritin to the receptor binding domain (RBD) and/or hep...

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Detalles Bibliográficos
Autores principales: Ma, Xiancai, Zou, Fan, Yu, Fei, Li, Rong, Yuan, Yaochang, Zhang, Yiwen, Zhang, Xiantao, Deng, Jieyi, Chen, Tao, Song, Zheng, Qiao, Yidan, Zhan, Yikang, Liu, Jun, Zhang, Junsong, Zhang, Xu, Peng, Zhilin, Li, Yuzhuang, Lin, Yingtong, Liang, Liting, Wang, Guanwen, Chen, Yingshi, Chen, Qier, Pan, Ting, He, Xin, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687490/
https://www.ncbi.nlm.nih.gov/pubmed/33275896
http://dx.doi.org/10.1016/j.immuni.2020.11.015