Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites

BACKGROUND: The complex composition of different cell types within a tissue can be estimated by deconvolution of bulk gene expression profiles or with various single-cell sequencing approaches. Alternatively, DNA methylation (DNAm) profiles have been used to establish an atlas for multiple human tis...

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Detalles Bibliográficos
Autores principales: Schmidt, Marco, Maié, Tiago, Dahl, Edgar, Costa, Ivan G., Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687708/
https://www.ncbi.nlm.nih.gov/pubmed/33234153
http://dx.doi.org/10.1186/s12915-020-00910-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687708/
https://www.ncbi.nlm.nih.gov/pubmed/33234153
http://dx.doi.org/10.1186/s12915-020-00910-4

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