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Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites

BACKGROUND: The complex composition of different cell types within a tissue can be estimated by deconvolution of bulk gene expression profiles or with various single-cell sequencing approaches. Alternatively, DNA methylation (DNAm) profiles have been used to establish an atlas for multiple human tis...

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Detalles Bibliográficos
Autores principales:	Schmidt, Marco, Maié, Tiago, Dahl, Edgar, Costa, Ivan G., Wagner, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687708/ https://www.ncbi.nlm.nih.gov/pubmed/33234153 http://dx.doi.org/10.1186/s12915-020-00910-4

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