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CloneSifter: enrichment of rare clones from heterogeneous cell populations

BACKGROUND: Many biological processes, such as cancer metastasis, organismal development, and acquisition of resistance to cytotoxic therapy, rely on the emergence of rare sub-clones from a larger population. Understanding how the genetic and epigenetic features of diverse clones affect clonal fitne...

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Detalles Bibliográficos
Autores principales: Feldman, David, Tsai, FuNien, Garrity, Anthony J., O’Rourke, Ryan, Brenan, Lisa, Ho, Patricia, Gonzalez, Elizabeth, Konermann, Silvana, Johannessen, Cory M., Beroukhim, Rameen, Bandopadhayay, Pratiti, Blainey, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687773/
https://www.ncbi.nlm.nih.gov/pubmed/33234154
http://dx.doi.org/10.1186/s12915-020-00911-3