Genetic feature engineering enables characterisation of shared risk factors in immune-mediated diseases

BACKGROUND: Genome-wide association studies (GWAS) have identified pervasive sharing of genetic architectures across multiple immune-mediated diseases (IMD). By learning the genetic basis of IMD risk from common diseases, this sharing can be exploited to enable analysis of less frequent IMD where, d...

Descripción completa

Detalles Bibliográficos
Autores principales: Burren, Oliver S., Reales, Guillermo, Wong, Limy, Bowes, John, Lee, James C., Barton, Anne, Lyons, Paul A., Smith, Kenneth G. C., Thomson, Wendy, Kirk, Paul D. W., Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687775/
https://www.ncbi.nlm.nih.gov/pubmed/33239102
http://dx.doi.org/10.1186/s13073-020-00797-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687775/
https://www.ncbi.nlm.nih.gov/pubmed/33239102
http://dx.doi.org/10.1186/s13073-020-00797-4

Ejemplares similares