Mesenchymal stem cells promote pancreatic β-cell regeneration through downregulation of FoxO1 pathway

BACKGROUND: Mesenchymal stem cells (MSC) are non-haematopoietic, fibroblast-like multipotent stromal cells. In the injured pancreas, these cells are assumed to secrete growth factors and immunomodulatory molecules, which facilitate the regeneration of pre-existing β-cells. However, when MSC are deli...

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Detalles Bibliográficos
Autores principales: Khatri, Rahul, Mazurek, Sybille, Petry, Sebastian Friedrich, Linn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687794/
https://www.ncbi.nlm.nih.gov/pubmed/33239104
http://dx.doi.org/10.1186/s13287-020-02007-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687794/
https://www.ncbi.nlm.nih.gov/pubmed/33239104
http://dx.doi.org/10.1186/s13287-020-02007-9

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