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Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer

BACKGROUND: Immune response against cancer has prognostic impact but its role in gastric cancer is poorly known. The aim of the study was to assess the prognostic significance of immune cell score (CD3+, CD8+), tumour immune escape (PD-L1, PD-1) and immune tolerance (Clever-1). METHODS: After exclus...

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Detalles Bibliográficos
Autores principales: Junttila, Anna, Helminen, Olli, Väyrynen, Juha P., Ahtiainen, Maarit, Kenessey, Istvan, Jalkanen, Sirpa, Mecklin, Jukka-Pekka, Kellokumpu, Ilmo, Kuopio, Teijo, Böhm, Jan, Mrena, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687887/
https://www.ncbi.nlm.nih.gov/pubmed/32943749
http://dx.doi.org/10.1038/s41416-020-01053-7