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A systematic review of meta-analyses assessing the validity of tumour response endpoints as surrogates for progression-free or overall survival in cancer

BACKGROUND: Tumour response endpoints, such as overall response rate (ORR) and complete response (CR), are increasingly used in cancer trials. However, the validity of response-based surrogates is unclear. This systematic review summarises meta-analyses assessing the association between response-bas...

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Detalles Bibliográficos
Autores principales: Cooper, Katy, Tappenden, Paul, Cantrell, Anna, Ennis, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687906/
https://www.ncbi.nlm.nih.gov/pubmed/32913287
http://dx.doi.org/10.1038/s41416-020-01050-w