Ntrk1 mutation co-segregating with bipolar disorder and inherited kidney disease in a multiplex family causes defects in neuronal growth and depression-like behavior in mice

Previously, we reported a family in which bipolar disorder (BD) co-segregates with a Mendelian kidney disorder linked to 1q22. The causative renal gene was later identified as MUC1. Genome-wide linkage analysis of BD in the family yielded a peak at 1q22 that encompassed the NTRK1 and MUC1 genes. NTR...

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Detalles Bibliográficos
Autores principales: Nakajima, Kazuo, Miranda, Alannah, Craig, David W., Shekhtman, Tatyana, Kmoch, Stanislav, Bleyer, Anthony, Szelinger, Szabolcs, Kato, Tadafumi, Kelsoe, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687911/
https://www.ncbi.nlm.nih.gov/pubmed/33235206
http://dx.doi.org/10.1038/s41398-020-01087-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687911/
https://www.ncbi.nlm.nih.gov/pubmed/33235206
http://dx.doi.org/10.1038/s41398-020-01087-8

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