Cargando…

Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway

Metabolic reprogramming to fulfill the biosynthetic and bioenergetic demands of cancer cells has aroused great interest in recent years. However, metabolic reprogramming for cancer metastasis has not been well elucidated. Here, we screened a subpopulation of breast cancer cells with highly metastati...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Yajing, Wang, Xiaoshuang, Li, Xiaoyu, Xu, Guangwei, Bai, Yuting, Wu, Jiayi, Piao, Yongjun, Shi, Yi, Xiang, Rong, Wang, Longlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688141/
https://www.ncbi.nlm.nih.gov/pubmed/33186350
http://dx.doi.org/10.1371/journal.pbio.3000872