Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model

Calcific aortic valve disease (CAVD) is a deadly disease that is rising in prevalence due to population aging. While the disease is complex and poorly understood, one well-documented driver of valvulopathy is serotonin agonism. Both serotonin overexpression, as seen with carcinoid tumors and drug-re...

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Detalles Bibliográficos
Autores principales: Joll, J. Ethan, Clark, Cynthia R., Peters, Christine S., Raddatz, Michael A., Bersi, Matthew R., Merryman, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688160/
https://www.ncbi.nlm.nih.gov/pubmed/33237915
http://dx.doi.org/10.1371/journal.pone.0238407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688160/
https://www.ncbi.nlm.nih.gov/pubmed/33237915
http://dx.doi.org/10.1371/journal.pone.0238407

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